The MacDonald Highlands are a series of highly affluent residential neighborhoods in Henderson, Nevada in the foothills of Black Mountain. In September 2007, Nancy Walton Laurie purchased a 17,878-square-foot residence in MacDonald Highlands for $17.5 million. The 89012 zip code, where the neighborhood is located, has the 7th highest per-capita income in the United States. The neighborhood is part of the Las Vegas Valley. The highlands are situated approximately 15 miles from the Las Vegas Strip and 20 miles from Downtown Las Vegas. It sits on the edges of the McCullough Mountains and overlooks much of Henderson and Greater Las Vegas including the Las Vegas Strip.

It is one of the highest points of Greater Las Vegas. Although guard-gated, and separated from other Henderson neighborhoods by the Dragonridge Country Club, it is bordered by the communities of Del Webb to the west, The Canyons to the southwest, McCullough Hills to the northeast and west, and Green Valley Ranch to the northwest.